BNM-III-170 trifluoroacetate ( —— )

产品货号. M12871 CAS No. 1859189-55-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BNM-III-170 trifluoroacetate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BNM-III-170 TFA 盐是一种小分子 CD4 模拟化合物，可增强疫苗在体内对抗 HIV-1 攻击的功效。
产品描述

BNM-III-170 TFA salt is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo; binds the HIV-1 gp120 Env and promotes conformational changes similar to those induced by CD4, exposing conserved Env elements to antibodies; synergizes with antibodies elicited by monomeric HIV-1 gp120 to protect monkeys from multiple high-dose intrarectal challenges with a heterologous simian-human immunodeficiency virus (SHIV).
体外实验

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体内实验

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同义词

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通路

Microbiology/Virology
靶点

HIV
受体

HIV
研究领域

——
适应症

——

CAS Number

1859189-55-1
分子量

674.958
分子式

C25H26ClF7N6O6
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

N1-(4-chloro-3-fluorophenyl)-N2-((1R,2R)-2-(guanidinomethyl)-5-((methylamino)methyl)-2,3-dihydro-1H-inden-1-yl)oxalamide bis(2,2,2-trifluoroacetate)

1. Madani N, et al. Nat Commun. 2018 Jun 18;9(1):2363.

计算器

产品手册

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